ESPACE – the expression and spatial analysis pancreas atlas consortium europe

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ESPACE – the HCA pancreas initiative

The Human Cell Atlas (HCA) is a global initiative which will create molecular reference maps of all human cells.

Three prior HCA early pilot studies of the pancreas have now come together to form the “Expression and Spatial analysis Pancreas Atlas Consortium Europe”, ESPACE.

Based on methods and standards for sample procurement, single cell profiling, spatial proteomics, and computational pipelines that were developed in these pilot studies, the ESPACE consortium will build a first version of the Human Cell Atlas of the Pancreas. In total, six projects have been selected for funding by the European Commission, each working on a different organ, and are to deliver their contributions to the HCA within the next two years.

Core activities overview

WP1 Tissue groups and sample procurement
Lead: Leiden University Medical Center (LUMC)

WP2 Single cell molecular profiling of the healthy human pancreas
Lead: Centre for Genomic Regulation (CRG)

WP3 Single cell molecular profiling of islets from T2D patients
Lead: The Research Fund of Hadassah Medical Organization (RFHMO)

WP4 Spatial analysis of cells and cell identity genes
Lead: Kungliga Tekniska Hoegskolan (KTH)

WP5 Data management – DCP Pancreas
Lead: Charité – Universitaetsmedizin Berlin (Charité)

WP6 Project management & Dissemination
Lead: Charité – Universitaetsmedizin Berlin (Charité)

News and events

Event30 September 2020

Coordinating research for building a Human Cell Atlas: second H2020-HCA cluster meeting

ESPACE is one of six projects that form the H2020-HCA cluster. They are all funded by the European Union within Horizon 2020 Research and Innovation Programme. Each of the projects...
Event01 February 2020

Starting to Build the Human Cell Atlas of the Pancreas: ESPACE Kick-Off Meeting in Berlin

On January 30 and 31, the Charité hosted delegates from the ESPACE partners for the project’s kick-off meeting in Berlin.
Event15 January 2020

Building the Foundations of a Human Cell Atlas: First Meeting of the H2020-HCA Consortia in Brussels

The European Commission invited the six H2020-HCA cluster projects – and among them the ESPACE team – to Brussels shortly after the project start on January 1, 2020.