ESPACE – the expression and spatial analysis pancreas atlas consortium europe

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ESPACE – the HCA pancreas initiative

The Human Cell Atlas (HCA) is a global initiative which will create molecular reference maps of all human cells.

Three prior HCA early pilot studies of the pancreas have now come together to form the “Expression and Spatial analysis Pancreas Atlas Consortium Europe”, ESPACE.

Based on methods and standards for sample procurement, single cell profiling, spatial proteomics, and computational pipelines that were developed in these pilot studies, the ESPACE consortium will build a first version of the Human Cell Atlas of the Pancreas. In total, six projects have been selected for funding by the European Commission, each working on a different organ, and are to deliver their contributions to the HCA within the next two years.

Core activities overview

WP1 Tissue groups and sample procurement
Lead: Leiden University Medical Center (LUMC)

WP2 Single cell molecular profiling of the healthy human pancreas
Lead: Centre for Genomic Regulation (CRG)

WP3 Single cell molecular profiling of islets from T2D patients
Lead: The Research Fund of Hadassah Medical Organization (RFHMO)

WP4 Spatial analysis of cells and cell identity genes
Lead: Kungliga Tekniska Hoegskolan (KTH)

WP5 Data management – DCP Pancreas
Lead: Charité – Universitaetsmedizin Berlin (Charité)

WP6 Project management & Dissemination
Lead: Charité – Universitaetsmedizin Berlin (Charité)

News and events

News23 November 2021

An interview with Dr Elisabetta Mereu

Already while conducting her undergraduate degree in mathematics, Dr Elisabetta Mereu knew that she wanted to apply her knowledge to more practical projects with a positive societal impact. In ESPACE,...
Event29 October 2021

ESPACE Annual Meeting 2021

The ESPACE consortium got together virtually on October 11-12 for the project’s second Annual Meeting. Representatives of all project partners participated in the two-day event to take stock of ESPACE’s progress to date and...
Event23 June 2021

Human Cell Atlas General Meeting to be held on June 28-30, 2021

The Human Cell Atlas (HCA) General Meeting will be held virtually on June 28-30, 2021. The meeting aims to provide a platform for HCA participants to share best practices and...