ESPACE – the expression and spatial analysis pancreas atlas consortium europe

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ESPACE – the HCA pancreas initiative

The Human Cell Atlas (HCA) is a global initiative which will create molecular reference maps of all human cells.

Three prior HCA early pilot studies of the pancreas have now come together to form the “Expression and Spatial analysis Pancreas Atlas Consortium Europe”, ESPACE.

Based on methods and standards for sample procurement, single cell profiling, spatial proteomics, and computational pipelines that were developed in these pilot studies, the ESPACE consortium will build a first version of the Human Cell Atlas of the Pancreas. In total, six projects have been selected for funding by the European Commission, each working on a different organ, and are to deliver their contributions to the HCA within the next two years.

Core activities overview

WP1 Tissue groups and sample procurement
Lead: Leiden University Medical Center (LUMC)

WP2 Single cell molecular profiling of the healthy human pancreas
Lead: Centre for Genomic Regulation (CRG)

WP3 Single cell molecular profiling of islets from T2D patients
Lead: The Research Fund of Hadassah Medical Organization (RFHMO)

WP4 Spatial analysis of cells and cell identity genes
Lead: Kungliga Tekniska Hoegskolan (KTH)

WP5 Data management – DCP Pancreas
Lead: Charité – Universitaetsmedizin Berlin (Charité)

WP6 Project management & Dissemination
Lead: Charité – Universitaetsmedizin Berlin (Charité)

News and events

News07 April 2022

H2020-HCA cluster publishes its second newsletter

We are delighted to share with you the second and most recent edition of the H2020-HCA Cluster on March 31, 2022 – you can read it here. The group consists...
Event23 March 2022

ESPACE Industry-Academia Webinar: Building a Human Cell Atlas of the Pancreas

Based on methods and standards for sample procurement, single cell profiling, spatial proteomics, and computational pipelines, the ESPACE consortium is building a first version of the Human Cell Atlas of...
News16 March 2022

The ESPACE Cloud – A snapshot

Dr. Sven Twardziok is a bioinformatician working at the Center of Digital Health at the Charité, where he’s leading a team focused on bioinformatics and data management. In this role,...