ESPACE – the expression and spatial analysis pancreas atlas consortium europe

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ESPACE – the HCA pancreas initiative

The Human Cell Atlas (HCA) is a global initiative which will create molecular reference maps of all human cells.

Three prior HCA early pilot studies of the pancreas have now come together to form the “Expression and Spatial analysis Pancreas Atlas Consortium Europe”, ESPACE.

Based on methods and standards for sample procurement, single cell profiling, spatial proteomics, and computational pipelines that were developed in these pilot studies, the ESPACE consortium will build a first version of the Human Cell Atlas of the Pancreas. In total, six projects have been selected for funding by the European Commission, each working on a different organ, and are to deliver their contributions to the HCA within the next two years.

Core activities overview

WP1 Tissue groups and sample procurement
Lead: Leiden University Medical Center (LUMC)

WP2 Single cell molecular profiling of the healthy human pancreas
Lead: Centre for Genomic Regulation (CRG)

WP3 Single cell molecular profiling of islets from T2D patients
Lead: The Research Fund of Hadassah Medical Organization (RFHMO)

WP4 Spatial analysis of cells and cell identity genes
Lead: Kungliga Tekniska Hoegskolan (KTH)

WP5 Data management – DCP Pancreas
Lead: Charité – Universitaetsmedizin Berlin (Charité)

WP6 Project management & Dissemination
Lead: Charité – Universitaetsmedizin Berlin (Charité)

News and events

News30 June 2022

H2020-HCA cluster publishes its third and final newsletter

Today, on the last official day of ESPACE, we published the third and final edition of the H2020-HCA Cluster Newsletter in collaboration with our sister projects in the cluster –...
News22 June 2022

ESPACE Final Meeting

On June 2, the ESPACE consortium held its final meeting as a hybrid meeting in Berlin and online. Two and a half years after the first kick-off meeting was held...
Event01 June 2022

Webinar recap: Building a Human Cell Atlas of the Pancreas

On 31 May 2022, ESPACE hosted its second Industry-Academia workshop. Close to 40 participants from the ESPACE consortium, other research centres and the industry attended this online event to learn...