ESPACE – the expression and spatial analysis pancreas atlas consortium europe

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ESPACE – the HCA pancreas initiative

The Human Cell Atlas (HCA) is a global initiative which will create molecular reference maps of all human cells.

Three prior HCA early pilot studies of the pancreas came together to form the “Expression and Spatial analysis Pancreas Atlas Consortium Europe”, ESPACE.

Based on methods and standards for sample procurement, single cell profiling, spatial proteomics, and computational pipelines that were developed in these pilot studies, the ESPACE consortium built a first version of the Human Cell Atlas of the Pancreas. In total, six projects had been selected for funding by the European Commission, each working on a different organ, and delivered their contributions to the HCA in 2022.

Core activities overview

WP1 Tissue groups and sample procurement
Lead: Leiden University Medical Center (LUMC)

WP2 Single cell molecular profiling of the healthy human pancreas
Lead: Centre for Genomic Regulation (CRG)

WP3 Single cell molecular profiling of islets from T2D patients
Lead: The Research Fund of Hadassah Medical Organization (RFHMO)

WP4 Spatial analysis of cells and cell identity genes
Lead: Kungliga Tekniska Hoegskolan (KTH)

WP5 Data management – DCP Pancreas
Lead: Charité – Universitaetsmedizin Berlin (Charité)

WP6 Project management & Dissemination
Lead: Charité – Universitaetsmedizin Berlin (Charité)

News and events

News30 June 2022

H2020-HCA cluster publishes its third and final newsletter

Today, on the last official day of ESPACE, we published the third and final edition of the H2020-HCA Cluster Newsletter in collaboration with our sister projects in the cluster –...
News30 June 2022

ESPACE presents at the Human Cell Atlas General Meeting 2022

With just one day left of the ESPACE funding period, Dr Timo Trefzer of the Berlin Institute of Health at Charité, Germany, and Dr Diego Balboa of Centre for Genomic...
News22 June 2022

ESPACE Final Meeting

On June 2, the ESPACE consortium held its final meeting as a hybrid meeting in Berlin and online. Two and a half years after the first kick-off meeting was held...